"Challenges of antiretroviral therapy among children aged 6 to 15 years in Kabarole district, 2009"

Introduction: HIV/AIDS is one of the leading causes of mortality among children in Kabarole district. It is however unknown how many children are on ART and there is very little documented evidence of the challenges faced by children aged 6 to 15 years on ART. Objectives of the study were to determine the proportion screened for HIV and on ART, estimate adherence levels and to establish factors associated with ART. Methods: A cross-sectional study was conducted to assess the challenges associated with ART among children aged 6 to 15 years in Kabarole district. Quantitative data were collected using a semi structured interviewer administered questionnaires and qualitative using Key Informant interviews. Adherence levels were assessed using self report information from caretakers and children 10 years and above. Logistic regression models were used to estimate odds ratios (OR’s) of adherence and their associated 95% confidence intervals. Results: By 30th April 2009, there were 478 children on ARV’s in the district. Of the 332 children in the study, 51% were girls and 65.4% were aged above 10 years. Using one month recall, 95.5% of the respondent’s adherence was 100%, 1.8% had 95-99% and 2.7% had adherence levels of less than 95%. On 3-day recall, 98.5% had 100% adherence, 1.5% had less than 95% adherence. Major challenges were a low proportion of children on ART, 42.5% of respondents failed to get transport at least once, 51% were orphans, co-trimoxazole stock outs at government facilities, lack of follow up and inadequate support supervision . Conclusions: Co-trimoxazole prophylaxis among children aged 6 to 15 years is a plausible predictor of adherence. Challenges to ART are numerous and solutions to them require a multi-faceted approach.

Author (s): 

Peter M Isabirye¹, N Kiwanuka¹, N Tumwesigye¹, J Kiguli¹ ¹-Makerere University School of Public Health

Presenter (s): 
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