case-control study

L-Tryptophan and Eosinophilia-Myalgia Syndrome ("EMS")

National epidemic of new syndrome in 1989 quickly traced to a commercial product. Case study addresses surveillance, bias, criteria for causation.

 

Objectives:

Investigation: 
Outbreak
Country: 
United States
Year: 
1990
Author (s): 

Leslie Swygert and Richard Dicker

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Tampons and Toxic Shock Syndrome

The initial outbreak investigations of toxic shock syndrome in 1980 using a series of matched case-control studies.  Case study focuses on matching, secondarily on surveillance.

 

Objectives:

  • Describe the concepts, applications, and limitations of matching in case-control studies;
  • Analyze matched case-control data; and
  • Discuss the issues involved in appropriate selection of controls in case-control studies.
Investigation: 
Outbreak
Country: 
United States
Year: 
1983
Author (s): 

Richard Dicker and Ruth Berkelman

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Oral Contraceptive Use and Ovarian Cancer ("OCs and Ovarian Cancer")

One of the first studies to address the association between oral contraceptive use and ovarian cancer; conducted by CDC using a multicenter case-control study design, 1980‑1982

 

Objectives:

Investigation: 
Other
Country: 
United States
Year: 
1981
Author (s): 

Richard Dicker and Peter Layde

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Cigarette Smoking and Lung Cancer

Based on the classic studies (both case-control study and cohort study of physician mortality) of Doll and Hill, 1950's; addresses study design, interpretation of measures of association, measures of impact, criteria of causation

Objectives

•    Define case-control and cohort studies and the advantages and disadvantages of each;

•    List some of the biases that might have affected these studies;

Investigation: 
Outbreak
Country: 
United Kingdom
Year: 
1973
Author (s): 

Clark Heath, Godfrey Oakley, David Erickson, and Howard Ory

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Risk factors for Severe Acute Respiratory Infection of pandemic H1N1 influenza infection in Hunan, China, 2009

Background: During 2009 pandemic H1N1 (pH1N1) influenza pandemic, increases in severe acute respiratory infection (sARI) were reported in Hunan Province, China. We conducted an investigation to identify risk factors for sARI among laboratory confirmed pH1N1 cases.

Year: 
2008
Author (s): 

X.S.Xing, L.J.Zhang, B.P. Zhu, H.H.Liu,1L.D.Gao, K.Hu, Z.Chen,

Presenter (s): 
Mr. Xue Sen Xing

Norovirus outbreak associated with contaminated bottled spring water in a boarding school: Zhejiang Province, China, 2010

Background: On April 22, 2010, a local hospital reported 29 students with acute gastroenteritis in a boarding school. We investigated this outbreak to identify the source of infection, mode of transmission and risk factors for infection.

Year: 
2009
Author (s): 

Jichuan Shen, J. Gao,H.L. Ma, L.J. Zhang, B.P. Zhu

Presenter (s): 
Mr. Ji Chuan Shen
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