Causation

A Multistate Outbreak of Cyclosporiasis

Local outbreak of cyclosporiasis was harbinger of multistate outbreak in 1996-1997; initially thought linked to strawberries, ultimately traced to raspberries from Guatemala.

 

Objectives:

Investigation: 
Outbreak
Country: 
Canada
Guatemala
United States
Year: 
2004
Author (s): 

Jeanette Stehr-Green

Add files

L-Tryptophan and Eosinophilia-Myalgia Syndrome ("EMS")

National epidemic of new syndrome in 1989 quickly traced to a commercial product. Case study addresses surveillance, bias, criteria for causation.

 

Objectives:

Investigation: 
Outbreak
Country: 
United States
Year: 
1990
Author (s): 

Leslie Swygert and Richard Dicker

Add files

An Epidemic of Thyrotoxicosis

Outbreak with unknown etiology and mode of transmission, crossing state lines, 1985; a nice wrap-up study, but domestic U.S. focus.

 

Objectives:

  • Define and perform calculations of sensitivity, specificity, predictive-value of a positive test, and predictive-value of a negative test;
  • Describe the relationship between prevalence and predictive value;
  • Discuss the trade-offs between sensitivity and specificity;
  • List the principles of a good screening program.
Investigation: 
Outbreak
Country: 
United States
Year: 
1987
Author (s): 

Frederic Shaw and Richard Dicker

Add files

Cigarette Smoking and Lung Cancer

Based on the classic studies (both case-control study and cohort study of physician mortality) of Doll and Hill, 1950's; addresses study design, interpretation of measures of association, measures of impact, criteria of causation

Objectives

•    Define case-control and cohort studies and the advantages and disadvantages of each;

•    List some of the biases that might have affected these studies;

Investigation: 
Outbreak
Country: 
United Kingdom
Year: 
1973
Author (s): 

Clark Heath, Godfrey Oakley, David Erickson, and Howard Ory

Add files
Syndicate content