outbreak investigation

An Epidemic of Thyrotoxicosis

Outbreak with unknown etiology and mode of transmission, crossing state lines, 1985; a nice wrap-up study, but domestic U.S. focus.

 

Objectives:

  • Define and perform calculations of sensitivity, specificity, predictive-value of a positive test, and predictive-value of a negative test;
  • Describe the relationship between prevalence and predictive value;
  • Discuss the trade-offs between sensitivity and specificity;
  • List the principles of a good screening program.
Investigation: 
Outbreak
Country: 
United States
Year: 
1987
Author (s): 

Frederic Shaw and Richard Dicker

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An Outbreak of Hemorrhagic Fever in Africa ("Ebola")

Investigation of the first recognized outbreak of Ebola hemorrhagic fever, in Zaire (now DRC), 1976; a practical outbreak investigation

 

Objectives:

Investigation: 
Outbreak
Country: 
Congo, the Democratic Republic of The
Year: 
1981
Author (s): 

David Heyman and Wayne Brown

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An Outbreak of Enteritis During a Pilgrimage to Mecca ("Mecca")

C. perfringens outbreak among members of the Kuwaiti medical mission during the pilgrimage to Mecca, 1979; a very straightforward outbreak investigation in a defined population with only 3 foods.

 

Objectives:

  • Define the term epidemic;
  • Create and understand the uses of a case definition;
  • Draw an epidemic curve;
  • Calculate food-specific attack rates;
  • List the steps in investigating an acute outbreak.
Investigation: 
Outbreak
Country: 
Saudi Arabia
Year: 
1980
Author (s): 

Fred Hoesly and Virgil Peavy

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Epidemic Measles in a Divided City ("Texarkana")

Measles outbreak in a community on the border of two states — the Arkansas side with required school immunization and high immunization rates, the Texas side without required immunization and low immunized rates, 1970.

Objectives

•    Discuss the advantages and disadvantages of using a sensitive and/or specific case definition in an epidemic investigation;

•    Calculate vaccine efficacy and discuss its interpretation; and

Investigation: 
Outbreak
Country: 
United States
Year: 
1971
Author (s): 

 Philip Landrigan, Lyle Conrad and John Witte

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An Outbreak of Jaundice in a Rural County ("West Branch Hepatitis") ("Omegaw County")

Community outbreak of hepatitis A associated with glazed pastries, 1968; an outbreak investigation in a community.

Objectives

•    Define the term “epidemic,”

•    Create a case definition and explain its importance in an outbreak investigation,

•    Draw and interpret an epidemic curve,

•    Calculate an attack rate,

Investigation: 
Outbreak
Country: 
United States
Year: 
1970
Author (s): 

Virgil Peavy, Fred Hoesly

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An Epidemic Disease in South Carolina

Based on Goldberger's studies of pellagra in the Southeastern United States in the 1910s; uses descriptive epidemiology and biologic categories of disease; presented as an unidentified illness (no clinical info) to focus thinking on epidemiologic features.  Good as either introductory (descriptive epi) or wrap-up (epidemiologic reasoning) exercise.

Objectives: 

• Apply the principles of descriptive epidemiology (time, place, person) in the investigation of a disease outbreak;

Investigation: 
Outbreak
Country: 
United States
Year: 
1947
Author (s): 

Alex Langmuir

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Project Excite Teaching Materials for Outbreak Investigations

This is a nice resource for teaching basic principles of outbreak investigation to children or to the general semi-educated public.  http://www.cdc.gov/excite/classroom/outbreak/index.htm

Rapid Response to a Cholera outbreak in Hodeidah governorate, Yemen 2010.

Introduction: Cholera remains a health problem in many parts of the word. Refugees, poverty, unsafe water supply and poor sanitation are an opportunity for spreading Vibrio cholera. Yemen’s proximity to the horn of Africa allows about 200-300 individuals to cross to Yemen daily, mainly through Hodeidah, on the red sea. This has resulted in spread of diseases to Yemen, including cholera. We investigated a cholera outbreak in Hodeidah in August 2010. This report summarizes the results of this investigation.

Year: 
2009
Author (s): 

Methaq Alsada Yemen (FETP)

Presenter (s): 
Al sada

Investigation of Seronegative Measles Infections during an Imported-Related Measles Outbreak - Rio Grande do Sul State, Brazil, 2010

Background: The World Health Organization recommends testing for measles immunoglobulin M (IgM) for laboratory confirmation. Measles IgM antibodies may be undetectable early in the infection or in previously immune individuals. We investigated IgM-seronegative measles episodes during an imported-related measles outbreak in southern Brazil.

Year: 
2010
Author (s): 

Priscila L. Leite 1, C. Costa 1, P. Reis 2, W. Araújo 1, T. Segatto 2, M. Bercini 3, J. Patzer 3, I. Menegolla 3, A. Pustai 4, R. Gralha 4, T. Ramos 5, G. Tertuliano 5, Z. Nunes 6, M. Costa 7, W. Santos 8, J. Lima 8, M. Siqueira 9, B. Flannery 10. 1 B

Presenter (s): 
Leite
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